List of publications – August 2021

 

 

Prof. Adit Ben Baruch

Chemotherapy Shifts the Balance in Favor of CD8+ TNFR2+ TILs in Triple-Negative Breast Tumors.

Baram T, Erlichman N, Dadiani M, Balint-Lahat N, Pavlovski A, Meshel T, Morzaev-Sulzbach D, Gal-Yam EN, Barshack I, Ben-Baruch A. Cells. 2021 Jun 8;10(6):1429. doi: 10.3390/cells10061429.

 

Prof. Judith Berman

Adaptive resistance mutations at supra-inhibitory concentrations independent of SOS mutagenesis.

Gutiérrez R, Ram Y, Berman J, Carstens Marques de Sousa K, Nachum-Biala Y, Britzi M, Elad D, Glaser G, Covo S, Harrus S. Mol Biol Evol. 2021 Jun 27:msab196. doi: 10.1093/molbev/msab196.

The fitness costs and benefits of trisomy of each Candida albicans chromosome.

Yang F, Todd RT, Selmecki A, Jiang YY, Cao YB, Berman J. Genetics. 2021 Jun 24;218(2):iyab056. doi: 10.1093/genetics/iyab056. PMID: 33837402

 

Prof. Eliora Ron

Surviving serum - the E. coli iss gene (increased serum survival) of extraintestinal pathogenic E. coli (ExPEC) is required for the synthesis of group 4 capsule.

Biran D, Sura T, Otto A, Yair Y, Becher D, Ron EZ. Infect Immun. 2021 Jun 28:IAI0031621. doi: 10.1128/IAI.00316-21.

 

Prof. Gideon Fleminger

The moonlighting activities of dihydrolipoamide dehydrogenase: Biotechnological and biomedical applications.

Fleminger G, Dayan A. J Mol Recognit. 2021 Jun 23:e2924. doi: 10.1002/jmr.2924.

 

Prof. Ehud Gazit

Self-Assembled Peptide Nano-Superstructure towards Enzyme Mimicking Hydrolysis.

Chen Y, Yang Y, Orr AA, Makam P, Redko B, Haimov E, Wang Y, Shimon LJW, Rencus-Lazar S, Ju M, Tamamis P, Dong H, Gazit E. Angew Chem Int Ed Engl. 2021 Jul 26;60(31):17164-17170. doi: 10.1002/anie.202105830.

 

Homocysteine fibrillar assemblies display cross-talk with Alzheimer's disease beta-amyloid polypeptide.

Sade Yazdi D, Laor Bar-Yosef D, Adsi H, Kreiser T, Sigal S, Bera S, Zaguri D, Shaham-Niv S, Oluwatoba DS, Levy D, Gartner M, Do TD, Frenkel D, Gazit E. Proc Natl Acad Sci USA. 2021 Jun 15;118(24):e2017575118. doi: 10.1073/pnas.2017575118.

 

Prof. Ehud Gazit and Prof. Tal Dvir

Nanoengineered Peptide-Based Antimicrobial Conductive Supramolecular Biomaterial for Cardiac Tissue Engineering.

Chakraborty P, Oved H, Bychenko D, Yao Y, Tang Y, Zilberzwige-Tal S, Wei G, Dvir T, Gazit E. Adv Mater. 2021 Jul;33(26):e2008715. doi: 10.1002/adma.202008715.

 

Prof. Ehud Gazit and Prof. Daniel Segal

Glucosylceramide Associated with Gaucher Disease Forms Amyloid-like Twisted Ribbon Fibrils That Induce α-Synuclein Aggregation.

Paul A, Jacoby G, Laor Bar-Yosef D, Beck R, Gazit E, Segal D. ACS Nano. 2021 Jul 2. doi: 10.1021/acsnano.1c02957.

 

Prof. Jonathan Gershuni

Motifier: An IgOme Profiler Based on Peptide Motifs Using Machine Learning.

Ashkenazy H, Avram O, Ryvkin A, Roitburd-Berman A, Weiss-Ottolenghi Y, Hada-Neeman S, Gershoni JM, Pupko T. J Mol Biol. 2021 Jul 23;433(15):167071. doi: 10.1016/j.jmb.2021.167071

 

Prof. Uri Gophna

Alteration in urease-producing bacteria in the gut microbiomes of patients with inflammatory bowel diseases.

Ryvchin R, Dubinsky V, Rabinowitz K, Wasserberg N, Dotan I, Gophna U. J Crohns Colitis. 2021 Jun 10:jjab101. doi: 10.1093/ecco-jcc/jjab101.

 

Prof. Anat Hershkovitz

A Metzincin and TIMP-Like Protein Pair of a Phage Origin Sensitize Listeria monocytogenes to Phage Lysins and Other Cell Wall Targeting Agents.

Boichis E, Sigal N, Borovok I, Herskovits AA. Microorganisms. 2021 Jun 18;9(6):1323. doi: 10.3390/microorganisms9061323.

 

Prof. Gerardo Lederkremer

Pridopidine reduces mutant huntingtin-induced endoplasmic reticulum stress by modulation of the Sigma-1 receptor.

Shenkman M, Geva M, Gershoni-Emek N, Hayden MR, Lederkremer GZ. J Neurochem. 2021 Jul;158(2):467-481. doi: 10.1111/jnc.15366.

 

Dr. Lior Mayo

Blood glutamate scavengers increase pro-apoptotic signaling and reduce metastatic melanoma growth in-vivo.

Goldshmit Y, Perelroizen R, Yakovchuk A, Banyas E, Mayo L, David S, Benbenishty A, Blinder P, Shalom M, Ruban A. Sci Rep. 2021 Jul 19;11(1):14644. doi: 10.1038/s41598-021-94183-8.

 

Dr. Vered Padler-Karavani

Biomolecular Recognition of the Glycan Neoantigen CA19-9 by Distinct Antibodies.

Borenstein-Katz A, Warszawski S, Amon R, Eilon M, Cohen-Dvashi H, Leviatan Ben-Arye S, Tasnima N, Yu H, Chen X, Padler-Karavani V, Fleishman SJ, Diskin R. J Mol Biol. 2021 Jul 23;433(15):167099. doi: 10.1016/j.jmb.2021.167099.

 

Prof. Dan Peer

Conformation-sensitive targeting of lipid nanoparticles for RNA therapeutics.

Dammes N, Goldsmith M, Ramishetti S, Dearling JLJ, Veiga N, Packard AB, Peer D. Nat Nanotechnol. 2021 Jun 17. doi: 10.1038/s41565-021-00928-x.

 

Lipid Nanoparticle RBD-hFc mRNA Vaccine Protects hACE2 Transgenic Mice against a Lethal SARS-CoV-2 Infection.

Elia U, Rotem S, Bar-Haim E, Ramishetti S, Naidu GS, Gur D, Aftalion M, Israeli M, Bercovich-Kinori A, Alcalay R, Makdasi E, Chitlaru T, Rosenfeld R, Israely T, Melamed S, Abutbul Ionita I, Danino D, Peer D, Cohen O. Nano Lett. 2021 Jun 9;21(11):4774-4779. doi: 10.1021/acs.nanolett.1c01284.

 

Design of SARS-CoV-2 hFc-Conjugated Receptor-Binding Domain mRNA Vaccine Delivered via Lipid Nanoparticles.

Elia U, Ramishetti S, Rosenfeld R, Dammes N, Bar-Haim E, Naidu GS, Makdasi E, Yahalom-Ronen Y, Tamir H, Paran N, Cohen O, Peer D. ACS Nano. 2021 Jun 22;15(6):9627-9637. doi: 10.1021/acsnano.0c10180.

Therapeutic inhibitory RNA in head and neck cancer via functional targeted lipid nanoparticles.

Kampel L, Goldsmith M, Ramishetti S, Veiga N, Rosenblum D, Gutkin A, Chatterjee S, Penn M, Lerman G, Peer D, Muhanna N. J Control Release. 2021 Jul 22:S0168-3659(21)00377-1. doi: 10.1016/j.jconrel.2021.07.034.

 

Prof. Gil Segal

A horizontally acquired Legionella genomic island encoding a LuxR type regulator and effector proteins displays variation in gene content and regulation.

Linsky M, Segal G. Mol Microbiol. 2021 Jun 13. doi: 10.1111/mmi.14770.

 

Prof. Adi Stern

Evidence for increased breakthrough rates of SARS-CoV-2 variants of concern in BNT162b2-mRNA-vaccinated individuals.

Kustin T, Harel N, Finkel U, Perchik S, Harari S, Tahor M, Caspi I, Levy R, Leshchinsky M, Ken Dror S, Bergerzon G, Gadban H, Gadban F, Eliassian E, Shimron O, Saleh L, Ben-Zvi H, Keren Taraday E, Amichay D, Ben-Dor A, Sagas D, Strauss M, Shemer Avni Y, Huppert A, Kepten E, Balicer RD, Netzer D, Ben-Shachar S, Stern A. Nat Med. 2021 Jun 14. doi: 10.1038/s41591-021-01413-7.

 

Dr. Yariv Wine

When a virus lies in wait

Taussig D, Wine Y.

Elife. 2021 Aug 4;10:e71121. doi: 10.7554/eLife.71121.

 

Prof. Itzhak Witz

Cancer drug resistance induced by EMT: novel therapeutic strategies.

De Las Rivas J, Brozovic A, Izraely S, Casas-Pais A, Witz IP, Figueroa A. Arch Toxicol. 2021 Jul;95(7):2279-2297. doi: 10.1007/s00204-021-03063-7.